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Boruta tackles the problem of selecting all-relevant variables that best discern between the phenotypic classes employing random forest classifiers and comparing the relevance of real variables to random synthetic probes

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For functional assays, mice were acclimatized for 1 week and then randomly divided into three groups ( n = 8 per group): blank (Con), Loperamide hydrochloride-induced constipation model (Lop), constipation mice pretreated with WECSL (Lop + WECSL) (Figure 1A)

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