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Dopaminergic agents cause a brief increase in GH release in normal subjects but paradoxically depress it in acromegalics

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Variant:Oil Control

In addition, the activation of vitamin B6 is dependent upon the FMN (the first of the two active forms of B2), and so in functional B2 deficiency vitamin B6 is not activated and this then affects the formation of the methylation precursor 5,10-methylene-THF, and will result in further reduction in the rate of methylation and hence B12 deficiency