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3.6 Ferroptosis: iron-dependent cell death Ferroptosis, a non-apoptotic form of regulated cell death involving iron ions and lipid peroxidation, is characterized primarily by the accumulation of lipid peroxides in the cell membrane ( Recent studies have indicated that ferroptosis, as an important mechanism of melanocyte destruction, not only directly leads to cell death but also intensifies the inflammatory response and immune dysregulation in vitiligo by enhancing oxidative stress and activating innate immune pathways ( + T cell response against melanocytes
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