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AOD-9604 is a modified fragment of human growth hormone (amino acids 176-191) isolated for its fat-metabolizing activity. It activates lipolysis, the breakdown of stored fat, without triggering the growth-promoting or blood sugar

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Research References Hyperglycemic action of synthetic C-terminal fragments of human growth hormone (Ng and Bornstein, Am J Physiol, 1978) Molecular and cellular actions of a structural domain of human growth hormone (AOD9401) on lipid metabolism in Zucker fatty rats (Ng et al., J Mol Endocrinol, 2000) The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice (Heffernan et al., Endocrinology, 2001) The conformational and biological analysis of a cyclic anti-obesity peptide from the C-terminal domain of human growth hormone (Ogru et al., J Pept Res, 2000) Human growth hormone fragment 176-191 peptide enhances the toxicity of doxorubicin-loaded chitosan nanoparticles against MCF-7 breast cancer cells (Habibullah et al., Drug Des Devel Ther, 2022) Published research on HGH Fragment 176-191 is indexed on PubMed